Science and Technology
Homer: I bet Einstein turned himself all sorts of colors before he invented the light bulb.
Chief Wiggum: Fat Tony is a cancer on this city. He is the cancer and I am the... uh... What cures cancer?
Homer: I see they have the Internet on computers now!
Homer: If I'm not a nuclear safety wha-cha-ma-gigger I don't know what I am.
Homer: Operator, give me the number for nine-one-one!
Homer: Lisa, come in here. In this house we obey the laws of thermodynamics!
Homer: The information superhighway showed the average person what some nerd thinks about Star Trek.
Bart: Wow! The universe is so boring.